Silent, but deadly--eliminating reservoirs of latent HIV.
نویسنده
چکیده
HIV treatment with highly active anti-retroviral therapy cannot eliminate latent reservoirs of HIV. In a recent paper, Root and Hamer describe a novel targeting mechanism for killing HIV-infected cells. They show that 5-helix (a gp41-binding protein) fused to a Pseudomonas exotoxin fragment can selectively kill cells displaying envelope proteins on their surface from a broad range of HIV strains.
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ورودعنوان ژورنال:
- Trends in biotechnology
دوره 21 10 شماره
صفحات -
تاریخ انتشار 2003